Positive Regulation of Apoptosis Signal-regulating Kinase 1 Signaling by ZPR9, a Zinc Finger Protein
نویسندگان
چکیده
From the 1 Department of Biochemistry, School of Life Sciences, Chungbuk National University, Cheongju 361-763 and the 2 Cell Therapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Republic of Korea Running Title: ZPR9 is a positive regulator of ASK1 Address correspondence to: Hyunjung Ha, Department of Biochemistry, School of Life Sciences, Chungbuk National University, Cheongju 361-763, Republic of Korea. Tel. (82) 43-261-3233; Fax. (82) 43-267-2306; E-mail: [email protected]
منابع مشابه
Zinc finger protein ZPR9 functions as an activator of AMPK-related serine/threonine kinase MPK38/MELK involved in ASK1/TGF-β/p53 signaling pathways
Murine protein serine-threonine kinase 38 (MPK38), an AMP-activated protein kinase (AMPK)-related kinase, has been implicated in the induction of apoptosis signal-regulating kinase 1 (ASK1)-, transforming growth factor-β (TGF-β)-, and p53-mediated activity involved in metabolic homeostasis. Here, zinc finger protein ZPR9 was found to be an activator of MPK38. The association of MPK38 and ZPR9 w...
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